Bienvenue sur le site de l'Institut Fédératif de Recherche n°66. .
Structures Fédératives de Recherche

L'avenir de L'IFR

Evaluation par l'AERES le 7 janvier 2010

Les Conférences :

La bibliothèque du Centre de Résonance Magnétique des Systèmes Biologiques (RMSB)

Mercredi 17 Mars à 11h00

Pr Tsutomu Chiba
Département de Gastroentérologie
Université de Kyoto, Japon

« Mechanism for inflammation-associated carcinogenesis. An important role of activation-induced cytide deaminase (AID) in induction of genetic abnormality »

Contact : Francis Mégraud, francis.megraud@chu-bordeaux.fr

Focus sur quelques publications récentes de l'IFR 66 :

Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cells.
Dumartin L, Quemener C, Laklai H, Herbert J, Bicknell R, Bousquet C, Pyronnet S, Castronovo V, Schilling MK, Bikfalvi A, Hagedorn M.(INSERM U 920)puce

Correlating global gene regulation to angiogenesis in the developing chick extra-embryonic vascular system.
Javerzat S, Franco M, Herbert J, Platonova N, Peille AL, Pantesco V, De Vos J, Assou S, Bicknell R, Bikfalvi A, Hagedorn M.
(INSERM U 920)puce
Lack of beta-catenin in early life induces abnormal glucose homeostasis in mice.
Dabernat S, Secrest P, Peuchant E, Moreau-Gaudry F, Dubus P, Sarvetnick N.
(INSERM U 876)puce
Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism.
Haurie V, Ménard L, Nicou A, Touriol C, Metzler P, Fernandez J, Taras D, Lestienne P, Balabaud C, Bioulac-Sage P, Prats H, Zucman-Rossi J, Rosenbaum J.
(INSERM U 889)puce

Une hypothèse originale puce
Lestienne P. (INSERM U 889)

Dernières Publications de L'IFR66

Laboratoire CNRS UMR 5234

Complete In Vitro Life Cycle of Trypanosoma congolense: Development of Genetic Tools.
Coustou V, Guegan F, Plazolles N, Baltz T.
PLoS Negl Trop Dis. 2010 Mar 2;4(3):e618.PMID: 20209144

Identification of a structural element of the hepatitis C virus minus strand RNA involved in the initiation of RNA synthesis.
Mahias K, Ahmed-El-Sayed N, Masante C, Bitard J, Staedel C, Darfeuille F, Ventura M, Astier-Gin T.
Nucleic Acids Res. 2010 Mar 1. [Epub ahead of print]PMID: 20194114

Activity of linezolid in an in vitro pharmacokinetic-pharmacodynamic model using different dosages and Staphylococcus aureus and Enterococcus faecalis strains with either a hypermutator phenotype or not.
Ba BB, Arpin C, Bikie Bi Nso B, Dubois V, Saux MC, Quentin C.
Antimicrob Agents Chemother. 2010 Jan 25. [Epub ahead of print]PMID: 20100878

Evolution of 2-long terminal repeat (2-LTR) episomal HIV-1 DNA in raltegravir-treated patients and in in vitro infected cells.
Reigadas S, Andréola ML, Wittkop L, Cosnefroy O, Anies G, Recordon-Pinson P, Thiébaut R, Masquelier B, Fleury H.
J Antimicrob Chemother. 2010 Mar;65(3):434-7. Epub 2010 Jan 5.PMID: 20051476

Laboratoire EA 3671

Chlamydia trachomatis infection in children: do not forget perinatal acquisition: a case report of a 7-year old girl, C. trachomatis infected, presumed sexually assaulted.
de Barbeyrac B, Benali L, Clerc M, Garapon S, Bébéar C, Gromb S.
J Forensic Leg Med. 2010 Feb;17(2):96-8. Epub 2009 Nov 20.PMID: 20129430 [PubMed - in process]

Laboratoire INSERM U 920

Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cells.
Dumartin L, Quemener C, Laklai H, Herbert J, Bicknell R, Bousquet C, Pyronnet S, Castronovo V, Schilling MK, Bikfalvi A, Hagedorn M.
Gastroenterology. 2010 Jan 14. [Epub ahead of print]PMID: 20080097 [PubMed - as supplied by publisher]

Correlating global gene regulation to angiogenesis in the developing chick extra-embryonic vascular system.
Javerzat S, Franco M, Herbert J, Platonova N, Peille AL, Pantesco V, De Vos J, Assou S, Bicknell R, Bikfalvi A, Hagedorn M.
PLoS One. 2009 Nov 17;4(11):e7856.PMID: 19924294 [PubMed - in process]Related articlesFree article

Laboratoire INSERM U 876

Neoadjuvant chemotherapy: a new selection criterion for candidate patients to surgery of low tumor burden metastases from malignant melanoma?
Jouary T, Legros C, Lalanne N, Versapuech J, Ezzedine K, Vergier B, Delaunay M, Velly JF, Taieb A.
Br J Dermatol. 2010 Feb 27. [Epub ahead of print]PMID: 20192958

The historical basis of a misconception leading to undertreating atopic dermatitis (eczema): facts and controversies.
Farhi D, Taïeb A, Tilles G, Wallach D.
Clin Dermatol. 2010 Jan-Feb;28(1):45-51.PMID: 20082950

Tissue inhibitor of matrix metalloproteinase-1 reduces phosphatidylserine exposure on activated and aged platelets.
Villeneuve J, Belloc F, Hugues M, Freyburger G, Solanilla A, Lepreux S, Combe C, Nurden AT, Dachary-Prigent J, Ripoche J.
Br J Haematol. 2010 Jan 8. [Epub ahead of print] No abstract available. PMID: 20064154

A Prevalent Mutation with Founder Effect in Xeroderma Pigmentosum Group C from North Africa.
Soufir N, Ged C, Bourillon A, Austerlitz F, Chemin C, Stary A, Armier J, Pham D, Khadir K, Roume J, Hadj-Rabia S, Bouadjar B, Taieb A, de Verneuil H, Benchiki H, Grandchamp B, Sarasin A.
J Invest Dermatol. 2010 Jan 7. [Epub ahead of print]PMID: 20054342

Laboratoire EA 2968

Therapeutic drug monitoring of mycophenolate mofetil and enteric-coated mycophenolate sodium in patients with systemic lupus erythematosus.
Djabarouti S, Duffau P, Lazaro E, Chapouly C, Greib C, Viallard JF, Pellegrin JL, Saux MC, Breilh D.
Expert Opin Pharmacother. 2010 Apr;11(5):689-99.PMID: 20210680

Determinants of Smoking Cessation Attempts among HIV-Infected Patients Results from a Hospital-Based Prospective Cohort.
Encrenaz G, Rondeau BV, Bonnet F, Lazaro E, Neau D, Dupon M, Dabis F, Mercié P, Chêne G; the ANRS CO3 Aquitaine Study Group (Groupe d'Epidémiologie Clinique du Sida en Aquitaine).
Curr HIV Res. 2009 Feb 16. [Epub ahead of print]PMID: 20158455

Bacterial Pneumonia among HIV-infected patients: decreased risk after tobacco smoking cessation. ANRS CO3 Aquitaine Cohort, 2000-2007.
Bénard A, Mercié P, Alioum A, Bonnet F, Lazaro E, Dupon M, Neau D, Dabis F, Chêne G; Groupe d'Epidémiologie Clinique du Sida en Aquitaine.
PLoS One. 2010 Jan 26;5(1):e8896.PMID: 20126646

Evolution of 2-long terminal repeat (2-LTR) episomal HIV-1 DNA in raltegravir-treated patients and in in vitro infected cells.
Reigadas S, Andréola ML, Wittkop L, Cosnefroy O, Anies G, Recordon-Pinson P, Thiébaut R, Masquelier B, Fleury H.
J Antimicrob Chemother. 2010 Mar;65(3):434-7. Epub 2010 Jan 5.PMID: 20051476

Laboratoire EA 4135

Structure-activity relationship of human liver-expressed antimicrobial peptide 2.
Hocquellet A, Odaert B, Cabanne C, Noubhani A, Dieryck W, Joucla G, Le Senechal C, Milenkov M, Chaignepain S, Schmitter JM, Claverol S, Santarelli X, Dufourc E, Bonneu M, Garbay B, Costaglioli P.
Peptides. 2009 Oct 21. PMID: 19852990 Related articles

Laboratoire INSERM U853

The sequential therapy regimen for Helicobacter pylori eradication.
Gisbert JP, Calvet X, O'Connor JA, Mégraud F, O'Morain CA.
Expert Opin Pharmacother. 2010 Mar 7. [Epub ahead of print]PMID: 20205606

[Bacterial resistance of Helicobacter pylori in the world in 2009]
Mégraud F, Corti R.
Acta Gastroenterol Latinoam. 2009 Dec;39(4):282-90. Spanish. No abstract available. PMID: 20178259

Sequential Therapy for Helicobacter pylori Eradication: A Critical Review.
Gisbert JP, Calvet X, Oʼconnor A, Mégraud F, Oʼmorain CA.
J Clin Gastroenterol. 2010 Jan 5. [Epub ahead of print]PMID: 20054285

Laboratoire EA 2406

Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.
Bonnart C, Deraison C, Lacroix M, Uchida Y, Besson C, Robin A, Briot A, Gonthier M, Lamant L, Dubus P, Monsarrat B, Hovnanian A.
J Clin Invest. 2010 Mar 1;120(3):871-82. doi: 10.1172/JCI41440. Epub 2010 Feb 22.PMID: 20179351

Genome-Wide Analysis of Cutaneous T-Cell Lymphomas Identifies Three Clinically Relevant Classes.
Laharanne E, Oumouhou N, Bonnet F, Carlotti M, Gentil C, Chevret E, Jouary T, Longy M, Vergier B, Beylot-Barry M, Merlio JP.
J Invest Dermatol. 2010 Feb 4. [Epub ahead of print]PMID: 20130593

CDKN2A-CDKN2B deletion defines an aggressive subset of cutaneous T-cell lymphoma.
Laharanne E, Chevret E, Idrissi Y, Gentil C, Longy M, Ferrer J, Dubus P, Jouary T, Vergier B, Beylot-Barry M, Merlio JP.
Mod Pathol. 2010 Jan 29. [Epub ahead of print]PMID: 20118908

Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling.
Bourane S, Garces A, Venteo S, Pattyn A, Hubert T, Fichard A, Puech S, Boukhaddaoui H, Baudet C, Takahashi S, Valmier J, Carroll P.
Neuron. 2009 Dec 24;64(6):857-70.PMID: 20064392 [

IRF4 Expression without IRF4 Rearrangement Is a General Feature of Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type.
Pham-Ledard A, Prochazkova-Carlotti M, Vergier B, Petrella T, Grange F, Beylot-Barry M, Merlio JP.
J Invest Dermatol. 2010 Jan 7. [Epub ahead of print] No abstract available. PMID: 20054341

Laboratoire UMR CNRS 5164

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.
Rebillard A, Jouan-Lanhouet S, Jouan E, Legembre P, Pizon M, Sergent O, Gilot D, Tekpli X, Lagadic-Gossmann D, Dimanche-Boitrel MT.
Eur J Cancer. 2010 Mar 3. [Epub ahead of print]PMID: 20202822

Variability and recombination of clinical human cytomegalovirus strains from transplantation recipients.
Faure-Della Corte M, Samot J, Garrigue I, Magnin N, Reigadas S, Couzi L, Dromer C, Velly JF, Déchanet-Merville J, Fleury HJ, Lafon ME.
J Clin Virol. 2009 Dec 16. [Epub ahead of print]PMID: 20022297 [PubMed - as supplied by publisher]Related articles

Laboratoire INSERM U 916

Synthesis and study of antiproliferative activity of novel thienopyrimidines on glioblastoma cells.
Pédeboscq S, Gravier D, Casadebaig F, Hou G, Gissot A, De Giorgi F, Ichas F, Cambar J, Pometan JP.
Eur J Med Chem. 2010 Feb 18. [Epub ahead of print]PMID: 20219270

[Identification of basal-like carcinomas in clinical practice: "triple zero/BRCA1-like" carcinomas.]
Vincent-Salomon A, Macgrogan G, Charaffe-Jauffret E, Jacquemier J, Arnould L.
Bull Cancer. 2010 Mar 3. [Epub ahead of print] French. PMID: 20197250

Questionnaires and instruments for a multidimensional assessment of the older cancer patient: What clinicians need to know?
Pallis AG, Wedding U, Lacombe D, Soubeyran P, Wildiers H.
Eur J Cancer. 2010 Feb 4. [Epub ahead of print]PMID: 20138506

Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study.
Lilly MB, Ottmann OG, Shah NP, Larson RA, Reiffers JJ, Ehninger G, Müller MC, Charbonnier A, Bullorsky E, Dombret H, Brigid Bradley-Garelik M, Zhu C, Martinelli G.
Am J Hematol. 2010 Mar;85(3):164-70.PMID: 20131302

Genome-Wide Analysis of Cutaneous T-Cell Lymphomas Identifies Three Clinically Relevant Classes.
Laharanne E, Oumouhou N, Bonnet F, Carlotti M, Gentil C, Chevret E, Jouary T, Longy M, Vergier B, Beylot-Barry M, Merlio JP.
J Invest Dermatol. 2010 Feb 4. [Epub ahead of print]PMID: 20130593

CDKN2A-CDKN2B deletion defines an aggressive subset of cutaneous T-cell lymphoma.
Laharanne E, Chevret E, Idrissi Y, Gentil C, Longy M, Ferrer J, Dubus P, Jouary T, Vergier B, Beylot-Barry M, Merlio JP.
Mod Pathol. 2010 Jan 29. [Epub ahead of print]PMID: 20118908

Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1.
Djavaheri-Mergny M, Maiuri MC, Kroemer G.
Oncogene. 2010 Jan 25. [Epub ahead of print]PMID: 20101204 [PubMed - as supplied by publisher]Related articles

Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy.
Lorin S, Pierron G, Ryan KM, Codogno P, Djavaheri-Mergny M.
Autophagy. 2010 Jan;6(1):153-4. Epub 2010 Jan 5.PMID: 19949306 [PubMed - in process]Related articles

Laboratoire INSERM U 889

MAPK scaffolding by BIT1 in the Golgi complex modulates stress resistance.
Yi P, Nguyên DT, Higa-Nishiyama A, Auguste P, Bouchecareilh M, Dominguez M, Bielmann R, Palcy S, Liu JF, Chevet E.
J Cell Sci. 2010 Mar 2. [Epub ahead of print]PMID: 20197408

A mutation in the 3'-UTR of the HDAC6 gene abolishing the post-transcriptional regulation mediated by hsa-miR-433 is linked to a new form of dominant X-linked chondrodysplasia.
Simon D, Laloo B, Barillot M, Barnetche T, Blanchard C, Rooryck C, Marche M, Burgelin I, Coupry I, Chassaing N, Gilbert-Dussardier B, Lacombe D, Grosset C, Arveiler B.
Hum Mol Genet. 2010 Mar 8. [Epub ahead of print]PMID: 20181727

Organization of the Sec61 Translocon, studied by High Resolution Native Electrophoresis.
Dejgaard K, Theberge JF, Heath-Engel H, Chevet E, Tremblay ML, Thomas DY.
J Proteome Res. 2010 Jan 29. [Epub ahead of print]PMID: 20112977

Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease.
Wong VW, Vergniol J, Wong GL, Foucher J, Chan HL, Le Bail B, Choi PC, Kowo M, Chan AW, Merrouche W, Sung JJ, de Lédinghen V.
Hepatology. 2010 Feb;51(2):454-62.PMID: 20101745

Liver myofibroblasts activate protein C and respond to activated protein C.
Gillibert-Duplantier J, Rullier A, Neaud V, Kisiel W, Rosenbaum J.
World J Gastroenterol. 2010 Jan 14;16(2):210-6.PMID: 20066740

Tissue inhibitor of matrix metalloproteinase-1 reduces phosphatidylserine exposure on activated and aged platelets.
Villeneuve J, Belloc F, Hugues M, Freyburger G, Solanilla A, Lepreux S, Combe C, Nurden AT, Dachary-Prigent J, Ripoche J.
Br J Haematol. 2010 Jan 8. [Epub ahead of print] No abstract available. PMID: 20064154

Pitfalls of liver stiffness measurement: A 5-year prospective study of 13,369 examinations.
Castéra L, Foucher J, Bernard PH, Carvalho F, Allaix D, Merrouche W, Couzigou P, de Lédinghen V.
Hepatology. 2009 Nov 9;51(3):828-835. [Epub ahead of print]PMID: 20063276

Laboratoire INSERM U 869

Identification of a structural element of the hepatitis C virus minus strand RNA involved in the initiation of RNA synthesis.
Mahias K, Ahmed-El-Sayed N, Masante C, Bitard J, Staedel C, Darfeuille F, Ventura M, Astier-Gin T.
Nucleic Acids Res. 2010 Mar 1. PMID: 20194114

The primary transcriptome of the major human pathogen Helicobacter pylori.
Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiss S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J.
Nature. 2010 Mar 11;464(7286):250-5. Epub 2010 Feb 17.PMID: 20164839

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie V, Durrieu-Gaillard S, Dumay-Odelot H, Da Silva D, Rey C, Prochazkova M, Roeder RG, Besser D, Teichmann M.

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CLUB ARN

Jeudi 18 Mars 2010

Programme

Lettre d'information de l'IFR66 n° 11
Mars 2010

Offre d'emploi

L’UMR 5231 « Imagerie Moléculaire et Fonctionnelle : de la Physiologie à la Thérapie »
CNRS/Université Bx 2 recrute
Un Ingénieur d’Etude en CDD

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